The monoclonal antibody 8D7 is cross reactive with human ASGPR. Immunohistochemistry analysis of paraffin-embedded mouse liver using ASGR1 antibody (A16766) at dilution of 1:100 (40x lens).Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.
The monoclonal antibody 8D7 recognizes a subunit-specific epitope of RHL-1 of rat ASGPR. The rat asialoglycoprotein receptor (ASGPR) consists of three polypeptide subunits: rat hepatic lectin (RHL)-1, RHL-2 and RHL-3. The mammalian hepatic ASGPR mediate the endocytosis and degradation of serum proteins from which terminal sialic residues have been removed. it is present on the sinusoidal and lateral plasma membranes but not on the bile canalicular membrane. The receptor is expressed on the surface of the hepatocytes in a polar manner, i. The asialoglycooprotein receptor (ASGPR) is a transmembrane glycoprotein (42 kDa) which mediates binding, internalization and degradation of extracellular glycoproteins that have exposed terminal galactose residues. If you cannot find the antibody you're looking for, contact us today to develop custom antibodies for specific targets, species and applications. This antibody functions as an ELISA detection antibody when paired with Rat Anti-Mouse ASGR1/ASGPR1 Monoclonal Antibody (Catalog MAB27551).
#Asgr1 antibody reactivity mouse verification
Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. īrowse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Choose from 1 of 25 ASGR1 antibodies, which have been validated in experiments with 5 publications and 63 images featured in our data gallery.īrowse primary antibodies for WB, Flow. Find the ASGR1 antibody that fits your needs. Mouse Reactivity: Rat Host Species: Rabbit Isotype: IgG Antibody Type: Polyclonal Antibody Research Area: Cell Biology.
These antibodies have been verified by Relative expression to confirm specificity to ASGR1. Anti-ASGR1 Antibody (CAB13279) from Assay Genie is a high quality antibody with reactivity against Human, Mouse, Rat and validated in WB applications. The blots were probed with Anti-CD31/PECAM-1 Rabbit Polyclonal Antibody (Product PA5-16301, 2 µg/mL) and detected by chemiluminescence using Goat anti-Rabbit IgG (H+L) Superclonal Secondary Antibody, HRP conjµgate. Our ASGR1 polyclonal, recombinant monoclonal and monoclonal antibodies are developed in Rabbit, Mouse and Goat. Western blot analysis was performed on membrane enriched extracts (30 µg lysate) of HEL 92.1.7 (Lane 1) and Jurkat (Lane 2). These antibodies target ASGR1 in Human, Mouse, Rat, Porcine samples. Antibodies that detect ASGR1 can be used in several scientific applications, including Western Blot, Immunohistochemistry, ELISA, Immunocytochemistry and Flow Cytometry.
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